GSK-1482160, CAS [[1001389-72-5]]

Product Overview

• Article Name: GSK-1482160, CAS [[1001389-72-5]]
• Biozol Catalog Number: MCE-HY-19888
• Supplier Catalog Number: HY-19888
• Alternative Catalog Number: MCE-HY-19888-5MG,MCE-HY-19888-10MG,MCE-HY-19888-10MMX1ML,MCE-HY-19888-100MG,MCE-HY-19888-50MG,MCE-HY-19888-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GSK-1482160 is an orally active and blood-brain barrier penetrant P2X7 receptor (P2X7R) negative allosteric modulator with pIC50s of 8.5 (human) and 6.5 (rat). GSK-1482160 reduces the efficacy of ATP at the P2X7 receptor without affecting its affinity, thereby inhibiting the release of IL-1beta. GSK-1482160 is an effective radioligand and can be labeled with radioactive isotopes like 11C or 18F to image P2X7R. GSK-1482160 can be used for the studies of chronic joint pain and chronic constriction injury (CCI)[1][2][3].

Product Properties

• Molecular Weight: 334.72
• Purity: 98.67
• CAS Number: [1001389-72-5]
• Formula: C14H14ClF3N2O2
• Target: Interleukin Related,P2X Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound