PG545 is a heparanase inhibitor and an FGF/VEGF inhibitor, with a Ki value of 6.1 nM against human heparanase, and Kd values of 8 nM, 390 nM, and 28.9 nM against human FGF-1, FGF-2, and VEGF, respectively. PG545 inhibits angiogenesis, tumor growth, and metastasis. PG545 is applicable in research related to melanoma and colorectal cancer[1].
Molecular Weight:
2363.82
CAS Number:
[1144492-69-2]
Formula:
C51H75Na13O60S13
Target:
FGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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