ITX5061 is an orally active type II non-competitive p38 MAPK inhibitor. ITX5061 increases HDL-C levels by inhibiting SR-BI activity. ITX5061 also moderately elevates ApoA-I levels. ITX5061 reduces early atherosclerotic lesions in the aortic arch of mice fed an atherogenic diet. ITX5061 can be used in the research of atherosclerosis[1].
Molecular Weight:
620.16
Purity:
99.69
CAS Number:
[1252679-52-9]
Formula:
C30H38ClN3O7S
Target:
p38 MAPK,Scavenger Receptor Class B type I (SR-BI)
Application Notes:
MCE Product type: Reference compound
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