JNJ-39220675 is a selective and brain-penetrating histamine H3 receptor antagonist with activity in regulating alcohol stimulation and reward. JNJ-39220675 is effective in reducing alcohol intake and preference in alcohol-preferring rats. JNJ-39220675 does not affect the ataxic effects of alcohol, the rate of alcohol elimination, or alcohol-induced nucleocapsid dopamine release[1].
Molecular Weight:
369.43
CAS Number:
[959740-39-7]
Formula:
C21H24FN3O2
Target:
Histamine Receptor
Application Notes:
MCE Product type: Reference compound
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