Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect[1][2].
Molecular Weight:
435.88
Purity:
99.32
CAS Number:
[1352610-25-3]
Formula:
C22H19ClFN7
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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