RO-3 is a potent, and orally active P2X3 and P2X2/3 antagonist with pIC50s of 5.9 and 7.0 for human homomultimeric P2X3 and heteromultimeric P2X2/3 receptors, respectively. RO-3 shows selectivity for P2X3 and P2X2/3 over all other functional homomultimeric P2X receptors (IC50 >10 µM at P2X1,2,4,5,7)[1].
Molecular Weight:
302.37
Purity:
97.32
CAS Number:
[1026582-88-6]
Formula:
C16H22N4O2
Target:
P2X Receptor
Application Notes:
MCE Product type: Reference compound
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