Tesirine intermediate-2 is the intermediate of Tesirine (HY-128952). Tesirine (SG3249), a pyrrole benzodiazepine (PBD) dimer, is a DNA small channel crosslinker with strong cytotoxicity. Tesirine can be used to synthesize Antibody-Drug Conjugates (ADCs), the warhead component of the payload is SG3199 (HY-101161), which has strong anticancer cell activity.
Molecular Weight:
793.98
Purity:
99.43
CAS Number:
[1430738-34-3]
Formula:
C40H55N5O10Si
Target:
DNA Alkylator/Crosslinker
Application Notes:
Reference compound
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