VEC6 (NSC 11435) is an inhibitor of VEZF1-DNA interaction and has the activity to recapitulate RhoB loss in ischemic retinopathy. VEC6 reduces pathological angiogenesis and promotes lymphangiogenesis. VEC6 plays a unique role in angiogenesis and lymphangiogenesis by regulating the expression of different sets of genes in endothelial cells. VEC6 has an inhibitory effect on VEZF1-mediated transcriptional activity, thereby affecting the proliferation and sprouting of endothelial cells[1].
Molecular Weight:
244.34
CAS Number:
[3431-16-1]
Formula:
C14H20N4
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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