2-PPA is a selective inhibitor of TMEM175 (IC50=32 µM) with activity in modulating lysosomal function. Acute inhibition of TMEM175 by 2-PPA increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. 2-PPA can be used in the study of Parkinsons disease[1].
Molecular Weight:
170.22
Purity:
99.98
CAS Number:
[21203-86-1]
Formula:
C11H10N2
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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