2-PPA is a lysosomal potassium and proton channel TMEM175 pore blocker. 2-PPA binds at a TMEM175 pore site to occlude potassium and proton ion permeation pathways. 2-PPA increases lysosomal macromolecule catabolism, accelerates macropinocytosis. 2-PPA binds to hepatic protein in covalent. 2-PPA can be used for the research of Parkinsons disease[1][2].
Molecular Weight:
170.22
Purity:
99.98
CAS Number:
[21203-86-1]
Formula:
C11H10N2
Target:
Potassium Channel,Proton Pump
Application Notes:
MCE Product type: Reference compound
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