5-CNAC is an orally active enhancer of absorption, with no pharmacological activity on its own. 5-CNAC can significantly enhance the absorption efficiency of the drug (such as salmon calcitonin) when administered together with it in the gastrointestinal tract. 5-CNAC binds reversibly and non-covalently to peptide drugs, protecting them from degradation by gastrointestinal enzymes, increasing their lipid solubility, promoting passive transcellular absorption, and not damaging the integrity of the intestinal epithelium. 5-CNAC can be used in the research of adjuvants for orally administered peptide agents[1][2].
Molecular Weight:
313.78
Purity:
99.49
CAS Number:
[204852-67-5]
Formula:
C15H20ClNO4
Target:
Others
Application Notes:
MCE Product type: Reference compound
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