Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 is 4 µM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model[1].
Molecular Weight:
427.51
Purity:
99.96
CAS Number:
[345288-49-5]
Formula:
C23H25NO5S
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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