DYRK2-IN-2, CAS [[2416195-65-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-402805
Supplier Catalog Number:
HY-402805
Alternative Catalog Number:
MCE-HY-402805-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
DYRK2-IN-2 (Compound C17) is a selective inhibitor of DYRK2, with its IC50 value being 40.3 nM. The inhibitory activity of DYRK2-IN-2 on DYRK1A (IC50 = 1842 nM), DYRK1B (IC50 = 1335 nM), DYRK4 (IC50 = 1931 nM), DYRK3 (IC50 = 112 nM), and CLKs (IC50 = 540-6496 NM) is relatively low. DYRK2-IN-2 inhibits the phosphorylation of Tau protein at Thr212 and shows moderate cytotoxicity in HT22 cells. DYRK2-IN-2 can be used in cancer research[1].
Molecular Weight:
384.49
CAS Number:
[2416195-65-6]
Formula:
C21H24N2O3S
Target:
CDK,DYRK,Tau Protein
Application Notes:
MCE Product type: Reference compound
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