(S,R,S)-AHPC-Me (hydrochloride), CAS [[1948273-03-7]] Preis auf Anfrage

Product Overview

• Article Name: (S,R,S)-AHPC-Me (hydrochloride), CAS [[1948273-03-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-42424
• Supplier Catalog Number: HY-42424
• Alternative Catalog Number: MCE-HY-42424-50MG,MCE-HY-42424-100MG,MCE-HY-42424-5G,MCE-HY-42424-1G,MCE-HY-42424-500MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: VHL ligand 2 (hydrochloride), E3 ligase Ligand 1

Product Description

(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 [2].

Product Properties

• Molecular Weight: 481.05
• Purity: 99.95
• CAS Number: [1948273-03-7]
• Formula: C23H33ClN4O3S
• Target: Ligands for E3 Ligase

Application Notes

• Application Notes: MCE Product type: Reference compound