ESI1 is a small molecule epigenetic silencing inhibitor. ESI1 can trigger the formation of nuclear condensates of key lipid metabolism regulators SREBP1/2, concentrating transcriptional co-activators to drive lipid/cholesterol biosynthesis. ESI1 can promote myelin regeneration in demyelinated animal models and facilitate de novo myelination on regenerating CNS axons, reversing age-related declines in cognitive abilities[1].
Molecular Weight:
355.82
Purity:
99.76
Formula:
C18H18ClN5O
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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