(1S,9R)-Ac-Exatecan is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 µM)[1].
Molecular Weight:
477.48
Formula:
C26H24FN3O5
Target:
Drug Intermediate
Application Notes:
MCE Product type: Reference compound
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