Dimethyl 2-oxoglutarate (Dimethyl alpha-ketoglutarate) is a cell-permeable derivative of 2-oxoglutarate and tricarboxylic acid cycle metabolite with antioxidant properties. Dimethyl 2-oxoglutarate inhibits Autophagy. Dimethyl 2-oxoglutarate prevents mitochondrial damage and reduces ROS production. Dimethyl 2-oxoglutarate alleviates Carbon tetrachloride (HY-Y0298)-induced liver fibrosis. Dimethyl-2-oxoglutaric acid can be used in the research of diseases such as Alzheimers disease, diabetes, and cardiomyopathy[1][2][3][4].
Molecular Weight:
174.15
Purity:
97.50
CAS Number:
[13192-04-6]
Formula:
C7H10O5
Target:
Autophagy,Drug Derivative,Endogenous Metabolite,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Biochemical Assay Reagents
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