Inixaciclib (NUV-422) is a blood-brain barrier-penetrant inhibitor of CDK2, CDK4 and CDK6. Inixaciclib inhibits cancer cell growth. Inixaciclib induces anti-tumor activity in xenograft models of glioblastoma, CDK4/CDK6 inhibitor-resistant HR+ HER2- metastatic breast cancer, and anti-androgen-resistant prostate cancer. Inixaciclib can be used for the research of relapsed or metastatic castration-resistant prostate cancer[1].
Molecular Weight:
480.55
Purity:
99.93
CAS Number:
[2370913-42-9]
Formula:
C26H30F2N6O
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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