CCG273441 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) with an IC50 value of 3.8 nM. CCG273441 is highly selective to GRK5 over GRK2 (IC50=4.8 µM) by binding Cys474, a GRK5 subfamily-specific residue, as a covalent handle[1].
Molecular Weight:
494.95
Purity:
98.78
CAS Number:
[2750414-35-6]
Formula:
C26H24ClFN4O3
Target:
G Protein-coupled Receptor Kinase (GRK)
Application Notes:
MCE Product type: Reference compound
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