Tesirine intermediate-1 is the intermediate of Tesirine (HY-128952). Tesirine (SG3249), a pyrrole benzodiazepine (PBD) dimer, is a DNA small channel crosslinker with strong cytotoxicity. Tesirine can be used to synthesize Antibody-Drug Conjugates (ADCs), the warhead component of the payload is SG3199 (HY-101161), which has strong anticancer cell activity.
Molecular Weight:
580.86
Purity:
99.55
CAS Number:
[1430738-05-8]
Formula:
C28H48N2O7Si2
Target:
DNA Alkylator/Crosslinker
Application Notes:
MCE Product type: Reference compound1
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