PLN-1474 (compound 1) is an orally active and selective alphanybeta1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or researching a fibrotic or cirrhotic disease or disorder.
Molecular Weight:
431.57
Purity:
99.35
CAS Number:
[2408065-32-5]
Formula:
C24H37N3O4
Target:
Integrin
Application Notes:
MCE Product type: Reference compound
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