Mavorixafor (AMD-070) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively. Mavorixafor can be used for the study of WHIM syndrome[1].
Molecular Weight:
349.47
Purity:
99.47
CAS Number:
[558447-26-0]
Formula:
C21H27N5
Target:
CXCR,HIV
Application Notes:
MCE Product type: Reference compound
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