Mavorixafor (AMD-070) hydrochloride is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor hydrochloride also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 nM and 9 nM, respectively. Mavorixafor hydrochloride can be used for the study of WHIM syndrome[1].
Molecular Weight:
385.93
Purity:
99.10
CAS Number:
[880549-30-4]
Formula:
C21H28ClN5
Target:
CXCR,HIV
Application Notes:
MCE Product type: Reference compound
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