DGAT-1 inhibitor 2 is an orally active DGAT-1 inhibitor with IC50 values of 15 nM and 9 nM for human DGAT-1 and rat DGAT-1, respectively. DGAT-1 inhibitor 2 increases ROS concentration, GRP78, and PERK protein abundance. DGAT-1 inhibitor 2 increases SREBF1, CPT1A, and MTTP mRNA in fatty acid-treated cells. DGAT-1 inhibitor 2 improves obesity[1][2].
Molecular Weight:
420.50
Purity:
95.33
CAS Number:
[942999-61-3]
Formula:
C24H28N4O3
Target:
Acyltransferase,HSP,PERK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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