Dactolisib (BEZ235) is an orally active and dual pan-class I PI3K and mTOR kinase inhibitor with IC50s of 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110alpha/p110gamma/p110delta/p110beta and mTOR, respectively. Dactolisib (BEZ235) inhibits both mTORC1 and mTORC2.
Molecular Weight:
469.54
Purity:
99.94
CAS Number:
[915019-65-7]
Formula:
C30H23N5O
Target:
Autophagy,mTOR,PI3K
Application Notes:
MCE Product type: Reference compound
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