Fiacitabine (NSC 382097, FIAC, FOAC) is a potent and highly selective anti-herpesvirus agent. Fiacitabine acts as an inhibitor of HSV DNA polymerase, with a Ki of 0.26 µM for HSV-1 and 0.42 µM for HSV-2, respectively. Fiacitabine can be efficiently phosphorylated by thymidine kinase encoded by the virus itself to generate FIACTP, an active triphosphate metabolite. Fiacitabine is applicable to research related to herpesvirus infections[1][2].
Molecular Weight:
371.10
Purity:
99.27
CAS Number:
[69123-90-6]
Formula:
C9H11FIN3O4
Target:
DNA/RNA Synthesis,EBV,HSV
Application Notes:
MCE Product type: Reference compound
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