Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4].
Molecular Weight:
514.99
Purity:
99.96
CAS Number:
[571189-11-2]
Formula:
C24H29N7O2.37/20ClH
Target:
CDK
Application Notes:
Reference compound
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