Bafetinib (Standard) is the analytical standard of Bafetinib. This product is intended for research and analytical applications. Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity[1][2][3].
Molecular Weight:
576.62
CAS Number:
[859212-16-1]
Formula:
C30H31F3N8O
Target:
Apoptosis,Bcr-Abl,Reference Standards,Src
Application Notes:
MCE Product type: Reference Standards
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