Crizotinib (acetate), CAS [[877399-53-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-50878B
Supplier Catalog Number:
HY-50878B
Alternative Catalog Number:
MCE-HY-50878B-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
PF-02341066 (acetate)
Crizotinib (PF-02341066) acetate is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib acetate inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib acetate is also a ROS1 inhibitor. Crizotinib acetate has effective tumor growth inhibition[1][2][3].
