L-873724 is a potent, orally bioavailable, selective and reversible[2] non-basic cathepsin K inhibitor, with IC50s of 0.2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively[1]. L-873724 also exhibits an IC50 of 0.5 nM for rabbit cathepsin K. L-873724 inhibits bone resorption[2].
Molecular Weight:
481.53
Purity:
98.93
CAS Number:
[603139-12-4]
Formula:
C23H26F3N3O3S
Target:
Cathepsin
Application Notes:
MCE Product type: Reference compound
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