Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer [1][2][5].
Molecular Weight:
446.90
Purity:
99.99
CAS Number:
[184475-35-2]
Formula:
C22H24ClFN4O3
Target:
Apoptosis,Autophagy,EGFR
Application Notes:
MCE Product type: Reference compound
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