Dovitinib-d8 is the deuterium labeled Dovitinib. Dovitinib (CHIR-258) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/FGFR3, VEGFR1/VEGFR2/VEGFR3 and PDGFRalpha/PDGFRbeta, respectively[1][2].
Molecular Weight:
400.48
CAS Number:
[1246819-84-0]
Formula:
C21H13D8FN6O
Target:
c-Fms,c-Kit,FGFR,FLT3,PDGFR,VEGFR
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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