PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.
Molecular Weight:
413.83
Purity:
99.90
CAS Number:
[918505-84-7]
Formula:
C17H14ClF2N3O3S
Target:
Raf
Application Notes:
MCE Product type: Reference compound
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