PLX-4720 (Standard) is the analytical standard of PLX-4720. This product is intended for research and analytical applications. PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.
Molecular Weight:
413.83
CAS Number:
[918505-84-7]
Formula:
C17H14ClF2N3O3S
Target:
Raf,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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