Galeterone, CAS [[851983-85-2]]

Product Overview

• Article Name: Galeterone, CAS [[851983-85-2]]
• Biozol Catalog Number: MCE-HY-70006
• Supplier Catalog Number: HY-70006
• Alternative Catalog Number: MCE-HY-70006-5MG,MCE-HY-70006-10MMX1ML,MCE-HY-70006-200MG,MCE-HY-70006-10MG,MCE-HY-70006-50MG,MCE-HY-70006-500MG,MCE-HY-70006-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: TOK-001, VN-124-1

Product Description

Galeterone (TOK-001) is a potent, orally active molecular glue degrader, which degrades androgen receptor (AR) and its splice variants (AR-Vs) and MAP kinase-interacting serine/threonine protein kinase Mnk1/2. Galeterone also functions as a CYP17 inhibitor (IC50 = 47 nM). Galeterone induces cell apoptosis. Galeterone inhibits tumor growth in human prostate cancer xenograft mouse models. Galeterone can be used for castration resistant prostate cancer (CRPC) and pancreatic ductal adenocarcinoma (PDAC) research[1][2].

Product Properties

• Molecular Weight: 388.55
• Purity: 99.87
• CAS Number: [851983-85-2]
• Formula: C26H32N2O
• Target: Androgen Receptor,Apoptosis,Cytochrome P450,MNK,Molecular Glues

Application Notes

• Application Notes: MCE Product type: Reference compound1