Alosetron ((Z)-2-butenedioate), CAS [[122852-43-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-70050B
Supplier Catalog Number:
HY-70050B
Alternative Catalog Number:
MCE-HY-70050B-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
GR 68755 ((Z)-2-butenedioate), GR 68755X ((Z)-2-butenedioate)
Alosetron (GR 68755) (Z)-2-butenedioate is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron (Z)-2-butenedioate is used for the research of irritable bowel syndrome (IBS). Alosetron (Z)-2-butenedioate blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron (Z)-2-butenedioate attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects[1][2].
Molecular Weight:
410.42
CAS Number:
[122852-43-1]
Formula:
C21H22N4O5
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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