GR 68755C (Standard), GR 68755 (Hydrochloride) (Standard), GR 68755X (Hydrochloride) (Standard)
Alosetron (Hydrochloride) (Standard) is the analytical standard of Alosetron (Hydrochloride). This product is intended for research and analytical applications. Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects[1][2].
Molecular Weight:
330.81
CAS Number:
[122852-69-1]
Formula:
C17H19ClN4O
Target:
5-HT Receptor,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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