Safinamide-d5 (FCE 26743-d5) is deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM)[1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?µM) than at resting (IC50=262?µM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al[2][3].
Molecular Weight:
307.37
Formula:
C17H14D5FN2O2
Target:
Isotope-Labeled Compounds,Monoamine Oxidase
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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