Isatoic anhydride is a single-adduct forming reagent and a monofunctional SHAPE reagent. Isatoic anhydride reacts with the 2-hydroxyl group of RNA nucleotides via a single reactive group to form a single adduct, without forming cross-links between nucleotides. In SHAPE-JuMP experiments, Isatoic anhydride serves as a control reagent for single-adduct formation, which is used to distinguish true cross-links from single-adduct formation[1].
Molecular Weight:
163.13
Purity:
99.26
CAS Number:
[118-48-9]
Formula:
C8H5NO3
Target:
Drug Intermediate
Application Notes:
MCE Product type: Reference compound1
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