BAY 61-3606, CAS [[732983-37-8]] Preis auf Anfrage

Product Overview

• Article Name: BAY 61-3606, CAS [[732983-37-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-76474
• Supplier Catalog Number: HY-76474
• Alternative Catalog Number: MCE-HY-76474-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

BAY 61-3606 is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM and an IC50 of 10 nM[1]. BAY 61-3606 reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell[2]. BAY 61-3606 induces a large decrease of Syk phosphorylation in K-rn cell lysates[3]. Bay 61-3606 sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells[4].

Product Properties

• Molecular Weight: 390.40
• Purity: 98.21
• CAS Number: [732983-37-8]
• Formula: C20H18N6O3
• Target: Apoptosis,Syk

Application Notes

• Application Notes: Reference compound