ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential[1].
Molecular Weight:
206.21
Purity:
95
CAS Number:
[1216897-16-3]
Formula:
C9H15FO4
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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