B-Raf IN 11 is a B-RafV600E mutant kinase inhibitor with an IC50 of 76 nM, and exhibits an IC50 of 238 nM against wild-type B-Raf kinase. B-Raf IN 11 inhibits the kinase activities of B-RafV600E mutant and wild-type B-Raf kinase. B-Raf IN 11 is applicable to relevant research on colorectal cancer[1].
Molecular Weight:
458.28
Purity:
99.46
CAS Number:
[918504-27-5]
Formula:
C17H14BrF2N3O3S
Target:
Raf
Application Notes:
MCE Product type: Reference compound
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