25-Hydroxytachysterol3 is the metabolite of Vitamin D3 (HY-15398). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor (VDR) and aryl hydrocarbon receptor (AhR), liver X receptor alpha/beta (LXR alpha/beta) and peroxisome proliferator-activated receptor gamma (PPARgamma), stimulates the expression of CYP24A1[1].
Molecular Weight:
400.64
Purity:
98.89
CAS Number:
[39932-44-0]
Formula:
C27H44O2
Target:
Aryl Hydrocarbon Receptor,LXR,PPAR,VD/VDR
Application Notes:
MCE Product type: Reference compound
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