MMAF intermediate 1 is an intermediate in the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1].
Molecular Weight:
448.55
Purity:
99.20
CAS Number:
[161485-82-1]
Formula:
C24H36N2O6
Target:
ADC Payload
Application Notes:
MCE Product type: Reference compound
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