BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Brutons tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
Molecular Weight:
524.59
Purity:
99.04
CAS Number:
[1431525-23-3]
Formula:
C29H24N4O4S
Target:
BMX Kinase,Btk
Application Notes:
MCE Product type: Reference compound1
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