Lenalidomide-d5 is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
Molecular Weight:
264.29
Purity:
99.32
CAS Number:
[1227162-34-6]
Formula:
C13H8D5N3O3
Target:
Apoptosis,Isotope-Labeled Compounds,Ligands for E3 Ligase,Molecular Glues
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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