Tolterodine ((R)-(+)-Tolterodine) is a mAChR inhibitor and substrate for cytochrome P450 enzymes. Tolterodine competitively binds acetylcholine, reduces sympathetic excitation, and inhibits involuntary bladder muscle contraction. Tolterodine restores the Nrf2/NF-kappaB signaling pathway, mediates protection against inflammatory response and ferroptosis. Tolterodine ameliorates LPS (HY-D1056)-induced reactive oxygen species production and lipid oxidation. Tolterodine can be used for the research of urinary tract infections and overactive bladder[1][2][3].
Molecular Weight:
325.49
Purity:
98.61
CAS Number:
[124937-51-5]
Formula:
C22H31NO
Target:
Cytochrome P450,mAChR
Application Notes:
MCE Product type: Reference compound
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