Malotilate (NKK 105), an orally active hepatotropic agent and an anti-fibrotic substance, selectively inhibits the 5-lipoxygenase (5-LOX) (IC50=4.7 µM). Malotilate prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes[1][2].
Molecular Weight:
288.38
Purity:
99.47
CAS Number:
[59937-28-9]
Formula:
C12H16O4S2
Target:
Lipoxygenase
Application Notes:
MCE Product type: Reference compound
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