Halofantrine, CAS [[69756-53-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-A0148
Supplier Catalog Number:
HY-A0148
Alternative Catalog Number:
MCE-HY-A0148-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
SKF-102886 (free base), WR-171669
Halofantrine (SKF-102886 hydrochloride, WR-171669 hydrochloride) is a blocker that delays the delayed rectifier potassium current by inhibiting human ERG channels, and it is a potent antimalarial agent with oral activity. Halofantrine inhibits the Cap1-dependent oxidative stress response of Candida albicans, suppresses ROS responses, and enhances the antifungal (Fungal) activity of oxidative damage agents. Halofantrine exhibits antifungal activity in the Galleria mellonella model, and shows antimalarial activity against Plasmodium strains both in vitro and in animal models. Halofantrine can be used in studies related to invasive candidiasis, falciparum malaria, and vivax malaria[1][2].
Molecular Weight:
500.42
CAS Number:
[69756-53-2]
Formula:
C26H30Cl2F3NO
Target:
Fungal,Parasite,Potassium Channel,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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