Methyl aminolevulinate, CAS [[33320-16-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-A0169
Supplier Catalog Number:
HY-A0169
Alternative Catalog Number:
MCE-HY-A0169-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Methyl aminolevulinate is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells, upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate is applicable to research related to actinic keratosis and basal cell carcinoma[1][2].
Molecular Weight:
145.16
CAS Number:
[33320-16-0]
Formula:
C6H11NO3
Target:
Photosensitizer,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
