Phosphatidylserine (Phospholipids) is a well-conserved anti-inflammatory and immunosuppressive signal. Phosphatidylserine is involved in membrane translocation and the activation of protein kinase C, participating in Akt signaling through its interaction with PIP3. The local exposure of Phosphatidylserine can interact with complement and other proteins, promoting microglial phagocytosis during critical periods of synaptic refinement. Phosphatidylserine can promote blood coagulation in the extracellular environment and acts as a eat me signal to clear out apoptotic cells. Phosphatidylserine can suppress inflammation in tissues by inducing TGF-beta secretion and inhibiting immune responses[1][2][3][4][5].
Molecular Weight:
788.10
Purity:
98
CAS Number:
[1446756-47-3]
Formula:
C42H78NO10P (for oleoyl)
Target:
Akt,TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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